![](http://172.25.11.96/wp-content/uploads/2022/04/DMacrophage_Microtubules_NL_01-copy-3-2.jpg)
Nikon AX R confocal
![](https://giif.gurdon.cam.ac.uk/wp-content/uploads/2022/07/Screenshot-2022-07-24-at-18.16.25-1024x930.png)
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Technology Focus
Confocal microscopes use a pinhole to reject out of focus light resulting in optical sectioning and an improved signal to noise ratio when compared to widefield fluorescence imaging. (See figure below – only in-focus light can pass through the pinhole to reach the detector).
![](http://172.25.11.96/wp-content/uploads/2022/04/Pinhole-Effect-Confocal-Microscope-1024x944-copy.png)
Confocal microscopes are ideal for imaging multi-labelled fluorescent samples up to around 100 microns in depth.
Figure credit – https://www.edinst.com/
For increased scanning speeds, the Nikon AX R confocal has a Resonant scanner achieving speeds around 20x faster than standard Galvano scanning confocals.
The field of view (FOV) on the Nikon AX R is larger as compared to our other available confocal systems.
The water pump allows multi-area, timelapse and high-content plate screening with the high NA water objectives by maintaining the meniscus across the entire plate and/or preventing evaporation issues.